Essays & Scientific Papers

Are SAR tables obsolete?

An editorial in Drug Discovery Today, entitled ‘Are SAR tables obsolete’ was published recently (Dec. 16.2016) on line questioning the utility of that icon of Medicinal Chemistry papers, ‘The SAR table’. The argument is made that currently, with all the knowledge available regarding the physicochemical properties of the compounds discussed in medicinal chemistry papers, it might be better to condense this information in some kind of 2D-diagram.